Alcohol-Induced Headache with Neuroinflammation: Recent Progress

Ethanol and other congeners in alcoholic beverages foods are known triggers of alcohol-induced headaches (AIHs). Recent studies implicate AIHs as an important underlying factor for neuroinflammation. Studies show the relationship between beverages, AIH agents, neuroinflammation, pathway they elicit. However, elucidating specific agents’ pathways scarce. Works reviewing their can give invaluable insights into substances’ patterns how be controlled. Hence, we reviewed current understanding agents affect neuroinflammation roles. upregulates transient receptor potential cation channel subfamily V member 1 (TRPV1) Toll-like 4 (TLR4) expression levels; both receptors trigger a response that promotes manifestation—the most common cause AIHs. Other such histamine, 5-HT, condensed tannins also upregulate TRPV1 TLR4, neuroinflammatory conditions, Data associating pathways, fermentation parameters help reduce or eliminate inducers create healthier beverages.